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Ionis Pharmaceuticals Inc (IONS) — Technical state

As of 2026-11-04 — re-computed nightly across the coverage universe. Closelooknet diary readings, not advice.

The Closelooknet read

  • Signal: Downtrend stack — Trades -15.9% vs the 50-day and -39.4% vs the 200-day average, 53.7% below the 52-week high and +2% off the 52-week low. Computed from daily closes. (as of 2026-11-04)
  • Trend: Ionis Pharmaceuticals Inc trades 15.9% below its 50-day and 39.4% below its 200-day moving average. (as of 2026-11-04)

Ionis Pharmaceuticals develops RNA-targeted medicines, treatments that alter how specific messenger RNA produces or suppresses proteins, mainly for rare and metabolic diseases. Its marketed products include SPINRAZA for spinal muscular atrophy, WAINUA for hereditary transthyretin amyloidosis, TRYNGOLZA for familial chylomicronemia syndrome, and several others such as DAWNZERA, QALSODY, TEGSEDI and WAYLIVRA.

The full read — the desk's view, the earnings record, peers and the company snapshot — is on the IONS overview. Research diary readings, not advice.

Downtrend stack

Trades -15.9% vs the 50-day and -39.4% vs the 200-day average, 53.7% below the 52-week high and +2% off the 52-week low. Computed from daily closes.

The moving-average stack

FAQ · from the current data · as of 2026-11-04

Quick answers

What is the current Closelooknet signal on IONS?

Downtrend stack — Trades -15.9% vs the 50-day and -39.4% vs the 200-day average, 53.7% below the 52-week high and +2% off the 52-week low. Computed from daily closes. As of 2026-11-04; the signal board re-computes across the coverage universe nightly. A research diary reading, not advice.

Is IONS above its 50-day and 200-day moving averages?

As of 2026-11-04, Ionis Pharmaceuticals Inc trades -15.9% below its 50-day and -39.4% below its 200-day average, with the 20-day -7.4% away.

How far is IONS from its 52-week high?

53.7% below the 52-week high and 2% above the 52-week low, as of 2026-11-04.

Related in the Closelooknet universe

then Biotechnology. Scored names rank on their Closelooknet score; names without one rank on trend state — above or below their 50- and 200-day averages — never on a score they do not carry.