Ionis Pharmaceuticals Inc (IONS) — Price History

As of 2026-10-30 — refreshed nightly from the Closelooknet data lake. Diary readings, not advice.

The Closelooknet read

Signal: Downtrend stack — Trades -11.2% vs the 50-day and -34.8% vs the 200-day average, 49.8% below the 52-week high and +3.4% off the 52-week low. Computed from daily closes. (as of 2026-10-30)
Trend: Ionis Pharmaceuticals Inc trades 11.2% below its 50-day and 34.8% below its 200-day moving average. (as of 2026-10-30)

Ionis Pharmaceuticals develops RNA-targeted medicines, treatments that alter how specific messenger RNA produces or suppresses proteins, mainly for rare and metabolic diseases. Its marketed products include SPINRAZA for spinal muscular atrophy, WAINUA for hereditary transthyretin amyloidosis, TRYNGOLZA for familial chylomicronemia syndrome, and several others such as DAWNZERA, QALSODY, TEGSEDI and WAYLIVRA.

The full read — the desk's view, the earnings record, peers and the company snapshot — is on the IONS overview; the trend detail on the technical tab. Research diary readings, not advice.

Daily prices

Date	Open	High	Low	Close	Chg %	Volume
2026-10-30	44.69	45.08	43.27	43.52	-1.96%	1,495,618
2026-10-29	45.57	45.84	44.04	44.39	-1.14%	1,833,848
2026-10-28	43.16	44.95	43.05	44.90	+2.14%	1,724,370
2026-10-27	43.23	44.10	43.02	43.96	+1.24%	2,376,841
2026-10-26	43.00	43.92	42.76	43.42	+1.14%	3,197,537
2026-10-23	43.80	43.80	42.58	42.93	-2.23%	3,015,008
2026-10-22	45.02	45.15	43.41	43.91	-0.81%	5,012,019
2026-10-21	45.55	45.76	44.26	44.27	-2.49%	2,269,836
2026-10-20	44.45	45.48	44.01	45.40	+2.30%	2,487,410
2026-10-19	43.33	44.54	43.00	44.38	+3.35%	3,098,987
2026-10-16	44.53	44.65	42.80	42.94	-2.67%	1,674,884
2026-10-15	43.58	44.71	43.42	44.12	+3.33%	2,484,999
2026-10-14	42.22	43.47	42.08	42.70	+0.76%	2,027,743
2026-10-13	43.55	43.58	42.36	42.38	-2.95%	2,978,032
2026-10-12	45.37	45.45	43.62	43.67	-3.56%	1,950,359
2026-10-09	43.21	45.72	43.12	45.28	+4.57%	4,862,320
2026-10-08	43.76	44.19	42.79	43.30	-1.95%	3,349,330
2026-10-07	43.75	44.26	43.53	44.16	+0.36%	2,943,620
2026-10-06	44.19	44.66	43.17	44.00	+1.15%	2,193,060
2026-10-05	43.75	43.96	42.63	43.50	-0.09%	2,871,832
2026-10-02	44.17	44.17	43.24	43.54	-1.05%	2,312,084
2026-10-01	44.63	45.95	43.96	44.00	-1.46%	2,030,329
2026-09-30	46.07	46.24	44.60	44.65	-2.70%	2,630,197
2026-09-29	45.53	46.46	45.39	45.89	+0.70%	3,885,842
2026-09-28	44.56	46.95	44.06	45.57	+2.40%	3,742,302
2026-09-25	44.24	45.28	43.62	44.50	+1.57%	6,202,420
2026-09-24	43.77	44.60	43.25	43.81	-0.27%	6,448,795
2026-09-23	46.23	46.41	43.01	43.93	-3.98%	3,535,786
2026-09-22	44.96	46.13	44.44	45.75	+1.89%	4,236,217
2026-09-21	44.95	45.25	44.20	44.90	+1.04%	4,521,358
2026-09-18	46.75	46.75	44.27	44.44	-4.94%	7,369,358
2026-09-17	46.68	47.42	45.75	46.75	+4.26%	4,079,573
2026-09-16	47.38	47.59	44.66	44.84	-5.10%	7,958,214
2026-09-15	51.37	51.37	46.72	47.25	-8.15%	6,812,465
2026-09-14	54.88	55.50	51.31	51.44	-5.11%	5,974,753
2026-09-11	55.94	56.16	54.16	54.21	-2.59%	2,175,778
2026-09-10	55.75	55.77	54.91	55.65	-0.66%	3,057,309
2026-09-09	56.38	56.96	55.70	56.02	-1.22%	3,037,757
2026-09-08	52.15	57.43	52.15	56.71	-2.38%	9,175,745
2026-09-04	58.36	58.96	57.78	58.09	-0.07%	2,671,092
2026-09-03	60.42	60.42	57.47	58.13	-5.22%	4,347,907
2026-09-02	60.25	61.77	59.77	61.33	+2.42%	1,845,866
2026-09-01	60.37	60.99	59.78	59.88	-0.80%	1,872,594
2026-08-31	61.06	61.06	59.70	60.36	-1.13%	2,017,160
2026-08-28	60.62	61.69	60.35	61.05	-2.21%	1,850,852
2026-08-27	63.48	63.48	62.34	62.43	-1.47%	1,625,581
2026-08-26	63.50	63.55	62.44	63.36	-0.33%	2,152,847
2026-08-25	62.53	64.19	62.19	63.57	+2.47%	2,435,239
2026-08-24	60.53	62.07	59.70	62.04	+3.85%	2,207,101
2026-08-21	59.64	60.91	59.06	59.74	+1.67%	2,723,906
2026-08-20	60.02	60.41	58.60	58.76	-3.36%	2,124,846
2026-08-19	60.11	61.35	59.61	60.80	+1.98%	3,137,560
2026-08-18	58.41	60.19	58.02	59.62	+1.69%	3,192,640
2026-08-17	57.11	58.74	56.41	58.63	+2.43%	2,000,182
2026-08-14	55.16	57.24	55.16	57.24	+2.45%	1,353,737
2026-08-13	56.50	56.81	55.56	55.87	-1.17%	1,220,460
2026-08-12	55.01	57.06	54.91	56.53	+2.00%	1,999,667
2026-08-11	56.79	57.16	55.37	55.42	-2.67%	2,407,128
2026-08-10	56.10	57.66	56.10	56.94	+0.67%	2,399,897
2026-08-07	54.73	56.60	54.40	56.56	+3.80%	2,009,277
2026-08-06	54.59	55.42	54.02	54.49	+0.55%	2,592,317
2026-08-05	55.17	55.36	53.58	54.19	-1.60%	2,122,267
2026-08-04	54.85	55.22	53.87	55.07	+1.06%	2,688,216
2026-08-03	52.66	54.54	52.16	54.49	+5.25%	3,212,858
2026-07-31	53.33	53.33	51.28	51.77	-2.83%	2,570,536
2026-07-30	53.92	54.04	52.65	53.28	-1.41%	2,875,352
2026-07-29	55.09	55.35	53.50	54.04	-2.28%	3,129,432
2026-07-28	56.56	56.56	54.00	55.30	-1.18%	2,805,274
2026-07-27	56.92	57.09	55.79	55.96	-1.04%	2,584,895
2026-07-24	56.32	57.36	56.19	56.55	+1.22%	3,094,731
2026-07-23	53.71	57.48	53.35	55.87	+3.44%	3,834,344
2026-07-22	51.16	54.06	50.01	54.01	+1.16%	8,732,966
2026-07-21	52.75	54.13	52.26	53.39	+0.83%	3,074,069
2026-07-20	54.47	54.80	52.82	52.95	-2.65%	2,167,064
2026-07-17	54.10	54.69	53.76	54.39	-0.48%	2,572,809
2026-07-16	53.95	55.98	53.38	54.65	-0.15%	3,805,259
2026-07-15	54.48	54.88	53.51	54.73	-0.36%	3,577,545
2026-07-14	55.80	56.45	54.53	54.93	-3.21%	4,700,265
2026-07-13	57.91	57.91	56.11	56.75	-2.58%	5,097,949
2026-07-10	64.27	64.44	58.20	58.25	-9.37%	11,444,106
2026-07-09	67.78	70.35	64.10	64.27	-23.90%	20,447,626
2026-07-08	85.56	86.74	83.92	84.46	-2.17%	2,280,833
2026-07-07	84.42	86.67	82.95	86.33	+3.79%	2,646,707
2026-07-06	82.11	84.01	81.19	83.18	+1.69%	1,847,437
2026-07-02	79.53	81.99	79.11	81.80	+3.30%	2,301,899
2026-07-01	79.13	79.48	77.95	79.19	-0.13%	1,442,398
2026-06-30	81.17	81.24	79.21	79.29	-1.74%	2,380,302
2026-06-29	81.00	82.53	79.95	80.69	-0.60%	2,806,623
2026-06-26	78.80	82.63	78.80	81.18	+3.63%	3,828,331
2026-06-25	76.69	79.55	76.25	78.34	+2.38%	2,583,536
2026-06-24	76.40	79.00	76.03	76.52	+0.70%	2,485,706
2026-06-23	75.89	77.31	75.77	75.99	+0.13%	1,405,415
2026-06-22	74.85	76.56	74.12	75.89	+2.39%	1,956,125
2026-06-18	75.00	75.66	73.50	74.12	-0.26%	2,984,374
2026-06-17	73.09	75.12	72.55	74.31	+1.67%	1,788,351
2026-06-16	73.93	73.95	72.30	73.09	-1.18%	1,801,390
2026-06-15	73.49	74.27	72.88	73.96	+0.93%	1,506,352
2026-06-12	73.82	74.35	72.57	73.28	-0.74%	1,964,868
2026-06-11	73.34	74.47	72.76	73.82	+0.68%	2,234,438
2026-06-10	74.43	75.85	72.83	73.32	-1.69%	1,595,746
2026-06-09	74.77	75.79	73.53	74.58	+1.41%	1,568,661
2026-06-08	74.33	74.43	73.14	73.54	-1.26%	1,620,750
2026-06-05	75.24	75.96	73.81	74.48	-0.87%	1,982,003
2026-06-04	74.01	75.88	73.82	75.13	+1.77%	1,241,131
2026-06-03	72.68	74.12	72.02	73.82	+1.16%	1,303,889
2026-06-02	74.85	75.22	72.56	72.97	-3.20%	2,086,205
2026-06-01	75.67	76.19	74.70	75.38	-1.46%	1,467,682
2026-05-29	77.54	78.10	76.39	76.50	-1.07%	1,675,660
2026-05-28	76.58	78.00	75.34	77.33	+1.10%	1,603,088
2026-05-27	76.24	77.40	76.23	76.49	+0.55%	1,341,369
2026-05-26	76.00	76.74	74.73	76.07	+0.67%	1,279,224
2026-05-22	75.71	76.80	75.00	75.56	-0.29%	1,579,206
2026-05-21	74.76	76.48	74.21	75.78	+0.96%	2,295,157
2026-05-20	74.67	75.69	73.97	75.06	+1.65%	2,005,309
2026-05-19	72.76	74.15	72.00	73.84	+1.82%	1,519,490
2026-05-18	74.58	74.78	71.93	72.52	-2.30%	2,211,491
2026-05-15	75.89	75.93	73.32	74.23	-1.92%	2,119,183
2026-05-14	79.00	79.19	75.31	75.68	-2.47%	1,798,305
2026-05-13	75.67	78.03	75.08	77.60	+2.33%	1,360,373
2026-05-12	76.03	77.13	75.38	75.83	+0.60%	1,408,887
2026-05-11	76.03	77.01	74.85	75.38	-0.44%	1,533,667
2026-05-08	76.45	77.40	75.24	75.71	-0.41%	1,656,234
2026-05-07	76.56	76.56	74.87	76.02	-1.08%	1,885,704
2026-05-06	75.62	77.42	75.29	76.85	+2.13%	1,799,880
2026-05-05	75.84	76.96	74.82	75.25	-0.27%	850,248
2026-05-04	75.28	76.00	74.47	75.45	+0.23%	1,689,516
2026-05-01	74.86	76.17	72.94	75.28	+0.70%	1,821,465
2026-04-30	74.91	77.76	73.81	74.76	-0.09%	2,430,344
2026-04-29	72.06	74.95	71.30	74.83	+4.25%	3,675,234
2026-04-28	72.71	73.10	71.17	71.78	-0.62%	2,396,291
2026-04-27	74.04	75.10	72.21	72.23	-1.42%	2,311,634
2026-04-24	74.09	74.51	72.33	73.27	-1.11%	1,817,367
2026-04-23	74.96	76.06	73.23	74.09	-0.99%	1,377,408
2026-04-22	75.22	75.44	74.00	74.83	+0.07%	2,024,007
2026-04-21	75.87	75.96	73.80	74.78	-0.12%	1,818,784
2026-04-20	75.50	75.62	74.58	74.87	-1.11%	1,106,829
2026-04-17	75.66	76.33	74.95	75.71	+0.60%	1,719,446
2026-04-16	76.42	76.53	73.91	75.26	-2.03%	1,873,899
2026-04-15	77.10	77.18	75.77	76.82	+0.08%	1,288,372
2026-04-14	74.88	77.38	74.88	76.76	+2.41%	1,595,277
2026-04-13	75.17	77.17	74.56	74.95	-0.29%	1,650,871
2026-04-10	77.02	77.14	74.53	75.17	-1.65%	1,581,578
2026-04-09	74.98	76.97	74.62	76.43	+1.93%	1,200,978
2026-04-08	76.07	76.48	74.30	74.98	+1.48%	1,266,771
2026-04-07	74.05	74.27	72.42	73.89	-0.59%	1,118,312
2026-04-06	74.54	75.47	73.56	74.33	-0.62%	1,440,939
2026-04-02	73.74	75.13	73.35	74.79	-0.45%	1,791,632
2026-04-01	75.70	76.48	74.79	75.13	+0.05%	1,664,978
2026-03-31	73.64	75.92	73.45	75.09	+3.54%	1,852,352
2026-03-30	73.12	73.21	71.48	72.52	+0.51%	2,045,479
2026-03-27	74.00	74.05	71.86	72.15	-2.82%	1,948,364
2026-03-26	72.25	75.63	70.50	74.24	+2.12%	3,884,070
2026-03-25	70.68	73.61	70.68	72.70	+4.33%	2,994,308
2026-03-24	70.27	70.64	68.90	69.68	-1.57%	1,844,404
2026-03-23	72.25	73.15	70.67	70.79	-0.28%	2,198,127
2026-03-20	71.51	72.59	70.50	70.99	-0.46%	2,920,652
2026-03-19	71.40	71.94	70.51	71.32	-0.49%	2,247,918
2026-03-18	71.84	72.30	70.92	71.67	-0.91%	2,180,298
2026-03-17	72.35	73.30	71.92	72.33	-0.01%	1,985,030
2026-03-16	71.58	72.88	71.29	72.34	+1.62%	3,231,515
2026-03-13	73.21	74.16	70.42	71.19	-1.59%	1,972,137
2026-03-12	74.30	74.30	72.01	72.34	-3.28%	2,461,797
2026-03-11	75.15	76.00	74.54	74.79	-1.15%	1,895,367
2026-03-10	75.36	77.03	74.51	75.66	+0.40%	2,785,714
2026-03-09	73.50	75.63	73.45	75.36	+1.78%	3,215,157
2026-03-06	73.97	75.16	73.15	74.04	-1.49%	1,904,239
2026-03-05	78.16	79.04	74.27	75.16	-5.40%	2,969,830
2026-03-04	79.16	80.06	77.67	79.45	+1.00%	2,503,118
2026-03-03	80.42	81.40	78.50	78.66	-4.03%	2,045,143
2026-03-02	79.27	82.75	79.27	81.96	+1.00%	3,098,359
2026-02-27	80.59	82.10	80.06	81.15	+0.68%	2,773,689
2026-02-26	80.32	82.44	78.92	80.60	-0.41%	3,330,043
2026-02-25	81.75	85.11	80.47	80.93	-5.29%	3,188,709
2026-02-24	84.66	85.47	83.45	85.45	+1.00%	2,384,832
2026-02-23	82.71	84.96	82.71	84.60	+1.74%	1,724,186
2026-02-20	82.85	83.63	81.64	83.15	+0.01%	2,832,477
2026-02-19	81.50	83.33	80.39	83.14	+1.13%	2,023,972
2026-02-18	81.26	83.06	80.98	82.22	+1.06%	1,950,099
2026-02-17	80.30	82.53	80.23	81.36	+0.94%	1,889,525
2026-02-13	81.18	82.56	79.78	80.60	-1.44%	1,931,201
2026-02-12	84.20	84.91	81.20	81.78	-3.05%	1,734,659
2026-02-11	84.19	84.96	82.00	84.35	+0.07%	1,104,176
2026-02-10	84.49	84.81	83.57	84.29	-0.59%	1,382,673
2026-02-09	86.13	86.49	84.61	84.79	-1.98%	1,738,204
2026-02-06	84.85	86.59	84.17	86.50	+3.62%	1,996,521
2026-02-05	84.51	86.74	82.89	83.48	-1.78%	2,677,732
2026-02-04	85.72	85.95	82.55	84.99	+0.47%	3,010,014
2026-02-03	83.00	85.45	83.00	84.59	+1.83%	1,461,130
2026-02-02	82.54	83.35	81.90	83.07	+0.48%	1,788,931
2026-01-30	83.48	83.70	82.21	82.67	-1.44%	2,518,439
2026-01-29	82.38	84.30	81.89	83.88	+2.39%	1,646,754
2026-01-28	81.92	82.63	81.63	81.92	-0.27%	1,732,406
2026-01-27	81.01	82.52	81.01	82.14	+1.41%	2,338,625
2026-01-26	79.49	81.28	79.24	81.00	+0.89%	1,700,602
2026-01-23	81.71	82.20	79.11	80.28	-1.84%	2,128,921
2026-01-22	79.62	82.19	78.89	81.79	+2.96%	3,695,674
2026-01-21	77.09	79.54	77.01	79.44	+2.46%	3,298,663
2026-01-20	75.03	77.99	74.20	77.53	+1.57%	4,894,345
2026-01-16	77.14	78.00	74.49	76.33	-1.14%	3,000,587
2026-01-15	79.25	79.75	77.15	77.21	-2.10%	1,409,021
2026-01-14	79.04	79.57	77.69	78.87	-0.77%	2,121,498
2026-01-13	82.24	82.57	78.61	79.48	-2.67%	1,885,179
2026-01-12	80.50	82.21	78.88	81.66	+1.69%	1,570,607
2026-01-09	82.17	83.23	79.30	80.30	-1.52%	2,668,760
2026-01-08	83.17	83.79	79.94	81.54	-1.96%	2,051,548
2026-01-07	82.50	86.15	82.40	83.17	+2.06%	3,889,646
2026-01-06	78.89	81.54	78.00	81.49	+3.77%	2,651,738
2026-01-05	79.18	79.42	76.08	78.53	-1.43%	1,448,687
2026-01-02	79.88	80.21	78.02	79.67	+0.71%	1,400,448
2025-12-31	78.78	79.84	78.63	79.11	+0.18%	1,096,900
2025-12-30	79.50	79.99	78.52	78.97	-1.26%	1,146,166
2025-12-29	79.73	80.04	78.74	79.98	+0.06%	1,077,894
2025-12-26	80.15	80.42	79.18	79.93	-0.89%	725,281
2025-12-24	80.33	81.02	80.33	80.65	+0.40%	480,227
2025-12-23	80.61	81.84	79.63	80.33	-1.24%	1,229,924
2025-12-22	79.26	82.09	79.09	81.34	+2.22%	2,257,844
2025-12-19	77.80	79.83	77.63	79.57	+2.50%	3,557,484
2025-12-18	77.39	78.16	76.69	77.63	+0.71%	1,765,565
2025-12-17	78.77	79.49	77.07	77.08	-1.65%	2,146,201
2025-12-16	79.41	79.56	77.16	78.37	-1.74%	1,959,742
2025-12-15	80.35	81.00	79.31	79.76	-1.31%	1,977,626
2025-12-12	79.19	80.92	78.50	80.82	+2.12%	1,468,893
2025-12-11	78.63	79.86	78.05	79.14	+0.65%	2,052,200
2025-12-10	79.38	79.71	77.79	78.63	-0.29%	2,659,323
2025-12-09	80.55	81.22	78.32	78.86	-3.25%	1,866,337
2025-12-08	82.12	82.86	81.18	81.51	-0.21%	1,553,583
2025-12-05	82.19	82.44	80.64	81.68	-0.16%	1,714,986
2025-12-04	81.90	83.61	81.44	81.81	-0.04%	2,317,827
2025-12-03	81.70	83.09	80.98	81.84	+0.65%	2,531,161
2025-12-02	82.38	82.69	80.00	81.31	-0.83%	2,454,566
2025-12-01	82.03	82.27	80.11	81.99	-0.89%	1,865,505
2025-11-28	82.59	82.95	81.67	82.73	+0.04%	852,943
2025-11-26	81.15	82.91	80.75	82.70	+2.19%	2,955,547
2025-11-25	78.52	81.20	78.33	80.93	+3.07%	2,543,172
2025-11-24	76.34	78.79	76.16	78.52	+3.19%	3,217,036
2025-11-21	73.00	76.31	73.00	76.09	+4.06%	2,076,032
2025-11-20	74.17	75.40	72.50	73.12	-1.19%	3,208,760
2025-11-19	74.55	75.00	71.83	74.00	-0.67%	3,620,815
2025-11-18	72.81	74.52	71.99	74.50	+1.69%	2,056,681
2025-11-17	70.70	74.42	70.69	73.26	+2.39%	3,504,705
2025-11-14	69.66	72.54	68.90	71.55	+2.45%	3,372,265
2025-11-13	72.56	73.05	68.22	69.84	-3.89%	11,502,846
2025-11-12	71.19	74.50	70.40	72.67	+0.30%	5,067,958
2025-11-11	69.32	72.79	68.55	72.45	+4.18%	2,268,649
2025-11-10	70.05	71.49	66.66	69.54	-5.45%	4,399,684
2025-11-07	73.58	75.00	72.36	73.55	-0.74%	2,332,419
2025-11-06	74.58	76.78	73.91	74.10	-0.78%	2,424,206
2025-11-05	72.14	75.08	71.48	74.68	+2.47%	2,259,305
2025-11-04	72.40	74.21	72.40	72.88	-1.05%	1,726,391
2025-11-03	74.77	75.25	71.95	73.65	-0.87%	2,576,035

Most recent 250 sessions, newest first.

Seasonal returns

Best month historically: Jun (+9.88%). Worst month: Jul (-5.29%). Based on 5 years of daily data (2022–2026).

Jan-0.25%
Feb-5.16%
Mar-5.27%
Apr+1.53%
May+2.32%
Jun+9.88%
Jul-5.29%
Aug+0.12%
Sep-3.74%
Oct+2.84%
Nov+1.20%
Dec-3.68%

FAQ · from the current price data · as of 2026-10-30

Quick answers

What is Ionis Pharmaceuticals Inc's (IONS) latest close?

43.52 on 2026-10-30, from the Closelook data lake's daily price record.

What is IONS's 52-week high and low?

86.74 high and 42.08 low over the trailing 52 weeks, as of 2026-10-30.

What is Ionis Pharmaceuticals Inc's strongest and weakest month historically?

Historically, IONS's strongest calendar month has been Jun (average +9.88%) and its weakest Jul (average -5.29%), based on 5 years of daily data (2022–2026).

How many years of seasonality does this cover?

5 years (2022–2026), computed from 1024 daily bars in the Closelook data lake.

What is the current Closelooknet signal on IONS?

Downtrend stack: Trades -11.2% vs the 50-day and -34.8% vs the 200-day average, 49.8% below the 52-week high and +3.4% off the 52-week low. Computed from daily closes. As of 2026-10-30. A research diary reading, not advice.

Is IONS above its 50-day and 200-day moving averages?

Ionis Pharmaceuticals Inc trades 11.2% below its 50-day and 34.8% below its 200-day moving average (0.8% below its 20-day). As of 2026-10-30.