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Crispr Therapeutics AG (CRSP) — chart, structure and Closelooknet read

The Closelooknet read

Crispr Therapeutics builds gene-editing medicines around its CRISPR/Cas9 platform, altering specific DNA sequences to treat serious diseases. Its lead product, Casgevy, edits a patient's own stem cells to treat sickle cell disease and beta-thalassemia, developed with partner Vertex Pharmaceuticals.

Detail below: the desk's view, the earnings record, peers and the company snapshot; daily prices on the price-history tab. Research diary readings, not advice.

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The desk on CRSP

What this diary said about Crispr Therapeutics AG, what it holds and what would change its view — in its own words, dated. Investment diary, not advice.

What we said

Signals for this name

Every Closelooknet reading that exists for CRSP, from the same nightly bakes the boards use. Research diary readings, not advice.

Mentioned on Closelooknet 2 pieces · newest: Strategy, “Portfolio Construction — The Barbell Architecture, Why the Middle Is Decay” (2026-05-23)

Mentioned on Closelooknet

Where CRSP appears in the diary — 2 pieces, newest first. Every link is our own writing.

Long reads

Weather around the name 3 macro readings: Money Temperature, Factor regime, Sovereign pressure

The weather around this name

Macro readings that apply by membership — the regime, the factor tape, the sector cell, the funding backdrop.

  • Money Temperature Composite 44/100 · S&P 500 fund at 48, above its 200-day averageEight instruments scored on position, momentum, volume, volatility and fragility — the regime every name trades inside. Temperature lab → 2026-11-05
  • Factor regime Defensive rotation — low-vol leading, regime-change watchMomentum against low volatility (SPMO / SPLV): below its 50-day trend, 73th percentile of the window, -21.7% over 20 sessions. Factor regime → 2026-11-04
  • Sovereign pressure Index -2.05 · down 2.95 over 21 sessionsG7 long-end yields, 10s30s and the slope — the funding weather for every balance sheet on this site. Sovereign pressure → 2026-11-05
How it trades on rate days beta 1.61 to TLT · on the worst bond days it fell more than the market

How it trades on rate days

How CRSP has moved when long-dated Treasury yields rise — measured against TLT, the 20+ year Treasury fund.

  • Beta to long bonds, 1 year 1.61 — moves strongly with bonds for every 1% move in TLT (20+ year Treasuries), Crispr Therapeutics AG moved 1.61% on average · correlation 0.27 · higher than 97% of US names
  • Beta, last 3 months 1.46 about the same as over the year
  • On the 10 worst bond days −2.60% on average against −0.74% for the S&P 500 the 10 sessions of the past year in which TLT fell most, i.e. long yields rose most
  • Latest of those days −0.11% TLT −1.29% that day 2026-09-24

Daily total returns from the adjusted price series; a TLT down day is a day long yields rose. Beta = the average move of the name for a 1% move in TLT. Past sensitivity, not a forecast. An investment diary, not a recommendation.

Who it is priced against Biotechnology · US · 8 names with week and year-to-date

Peer group

Biotechnology · US

This name carries no Closelooknet score, so its cohort ranks on trend state — distance to the 50- and 200-day averages — never on a score it does not have.

Compared against CRSP on the nightly bakes; the Peers tab ranks the cohort on the Closelooknet scores where it exists.

Company snapshot — Crispr Therapeutics AG

CRSP in five paragraphs: what it makes and sells, where it sits in the Closelooknet stack, who it is priced against, why we track it, what we watch. Research diary, not advice.

What it does
Crispr Therapeutics builds gene-editing medicines around its CRISPR/Cas9 platform, altering specific DNA sequences to treat serious diseases. Its lead product, Casgevy, edits a patient's own stem cells to treat sickle cell disease and beta-thalassemia, developed with partner Vertex Pharmaceuticals. The pipeline extends into CAR T cell therapies for cancer and autoimmune disease, in-vivo editing for cardiovascular targets, and a stem-cell approach to type 1 diabetes. It is headquartered in Zug, Switzerland.
Where it sits in the stack
Crispr Therapeutics carries no seat in our index and sits outside the AI build-out stack entirely; it belongs to our healthcare universe, in the biotechnology sleeve, as a gene-editing developer rather than an infrastructure or compute name.
Who it is priced against
Closelooknet has not set a peer group for this name; the comparison the market draws most often is with Intellia Therapeutics, another CRISPR-based drug developer.
Why Closelooknet tracks it
It holds no index seat and carries no Closelooknet score. Its only diary mentions come from strategy and heresy pieces citing the CRSP database behind Bessembinder's stock-return study, a reference to the academic dataset rather than coverage of the company itself.
What the diary watches
The diary watches how the Vertex partnership evolves and whether Casgevy's uptake and the wider pipeline's clinical progress eventually earn the name its own index seat and score.

Crispr Therapeutics AG (CRSP) trades on US exchanges.

Written from the company’s public profile and Closelooknet’s own readings, 2026-09-17. Descriptive, refreshed with the registry; corrections welcome via the imprint. closelook.net is an investment research diary — market structure, index membership and scores are our own readings, not investment advice. Related: index compare · sector dispersion · scanner.

The Street on this name 1 analyst action on the wire · latest: price target by Wells Fargo, 2026-11-04

The Street on this name

Analyst actions and the latest print for CRSP from the Closelooknet wires — third-party opinions on the record, not our readings.

  • Price target Wells Fargo — target 70 Target set to $70 (+40% to spot) 2026-11-04

1 action on the analyst wire since 2026-08-13: 1 target change. Analyst wire → · Earnings wire →

FAQ · from the current data · as of 2026-11-06

Quick answers

What is Crispr Therapeutics AG (CRSP)?

Crispr Therapeutics AG trades as CRSP on the US exchange (US) in the Closelooknet research universe, as of the registry build of 2026-11-06.

Is CRSP in a Closelooknet index?

Not currently — Crispr Therapeutics AG is tracked in the Closelooknet research universe but is not a constituent of a Closelooknet functional index as of 2026-11-06.

Where does CRSP trade against its moving averages?

Crispr Therapeutics AG trades 9.2% below its 50-day and 8.0% below its 200-day moving average (4.4% below its 20-day). As of 2026-11-05 — a technical state from the nightly Closelooknet bake, not advice. The Technical tab carries the full row.

How does Crispr Therapeutics AG compare with its peers?

Against its peer group (Biotechnology · US), Crispr Therapeutics AG (CRSP) sits 23.5% below its 52-week high, 9.2% below its 50-day average; Halozyme Therapeutics Inc (HALO) is 8.2% below, BeOne Medicines AG (ONC) is 4.4% below, argenx NV ADR (ARGX) is 16.6% below, as of 2026-11-05. Put any of them next to CRSP in the chart grid (2×1 or 2×2) and the page lays the companies side by side: performance, trend, valuation, margins and our money-flow reading.

How does Crispr Therapeutics AG trade when bond yields rise?

Over the past year Crispr Therapeutics AG had a beta of 1.61 to TLT, the long-dated Treasury fund — it moves strongly with bonds, higher than 97% of US names. On the 10 sessions in which long bonds fell most it moved −2.60% on average, against −0.74% for the S&P 500. As of 2026-11-05; The "How it trades on rate days" block on this page carries the lines.

Where has Closelooknet written about Crispr Therapeutics AG?

Crispr Therapeutics AG appears in 2 Closelooknet pieces as of 2026-11-06, most recently Strategy: Portfolio Construction — The Barbell Architecture, Why the Middle Is Decay (2026-05-23); Heresy: US Equities — Don’t Buy U.S. Stocks · Closelooknet Heresy (2026-05-08). What Closelooknet said most recently: Bessembinder's 2018 paper showed that, of the US common stocks in the CRSP database from 1926 to 2016, the best-performing 4% accounted for the entire net wealth ever created — the other 96% collectively matched one-month Treasury bills. (Strategy, 2026-05-23). The "Mentioned on Closelooknet" block on this page lists the long reads, the reference entries and the dailies that name it.

What does Crispr Therapeutics AG do?

Crispr Therapeutics builds gene-editing medicines around its CRISPR/Cas9 platform, altering specific DNA sequences to treat serious diseases. Its lead product, Casgevy, edits a patient's own stem cells to treat sickle cell disease and beta-thalassemia, developed with partner Vertex Pharmaceuticals. The pipeline extends into CAR T cell therapies for cancer and autoimmune disease, in-vivo editing for cardiovascular targets, and a stem-cell approach to type 1 diabetes. Closelooknet has not set a peer group for this name; the comparison the market draws most often is with Intellia Therapeutics, another CRISPR-based drug developer. (Company snapshot of 2026-09-17.)

Where does Crispr Therapeutics AG sit in the AI build-out?

Crispr Therapeutics carries no seat in our index and sits outside the AI build-out stack entirely; it belongs to our healthcare universe, in the biotechnology sleeve, as a gene-editing developer rather than an infrastructure or compute name. It holds no index seat and carries no Closelooknet score. Its only diary mentions come from strategy and heresy pieces citing the CRSP database behind Bessembinder's stock-return study, a reference to the academic dataset rather than coverage of the company itself. (Company snapshot of 2026-09-17.)

What has Wall Street done on Crispr Therapeutics AG recently?

The most recent analyst action on Crispr Therapeutics AG on the Closelooknet wire is a price target by Wells Fargo on 2026-11-04 (target 70). 1 action on the analyst wire since 2026-08-13: 1 target change. Analyst actions are third-party opinions recorded by the wire, not Closelooknet readings. The “The Street on this name” block on this page lists the moves; the full feeds are the analyst wire and the earnings wire.

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A live price chart with SMA overlays and drawing tools for CRSP, performance metrics, index-membership context and the Closelooknet structure read — an investment research diary view, not investment advice.

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Related in the Closelooknet universe

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